Still struggling with the Joystick Setup

[Whizkid]

I've looked at most of the X-52 setups and info. and nowhere can I find advice on how to start the process. Here are my questions.
1. Do I have to delete all the ingame Control inputs in order to apply inputs to the Stick through the Profile Editor?
2. If I have both inputs working will this mess them both up?
3. If I delete all the Control Inputs ingame can I easily reset them if I need to?
4. Which is the preferred method of Control, Profile Editor or using the ingame Controls?
5. I'm using TIR so does this free up the tophats for other uses?
6. Which X-52 Profile available is considered the best for CLOD?

Now I have Win7/64 and Mod 4.0, I can only applaud all the people who have lifted this sim from near-death to one of the most enjoyable flight sims on the market. just looking at that opening screen with the Anson flying over the lakes and the setting (rising?) sun in the background quickens my heart and makes me say, "Well done, all of you, and Thank You!"