Good question...I have mine setup as follows on the same card :
1. Power management = max performance
2. CUDA = None
3. Texture quality = Performance
4. Triliniar optimisation = ON
5. Vsinc = ON
6. Anisotropic filtering = Application Controlled
7. I use Inject FXAA, files on, not enabled in the drivers!
Results are better than on my old 480GTX!
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