I only have an onboard sound setup.I have a usb headset/mic.I have Teamspeak set to hear the voice over the headset and the game over the speakers.
However in the Teamspeak settings under the options you can set what you want the headset to use and what you want the mic to use.So you can mix and match if you so desire.So even with phono plugs(non usb) and onboard and soundcard you can split the game sound from the headset.
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