I upgraded from i7 920 to a i7 2600k overclocked to 4.5 (basically the same as i5 2500k for this game) and I noticed a significant increase in fps and stutter reduction. I think this is something that is safe to upgrade immediately.
Wouldn't be so concerned about RAM as long as you have at least 4GB DDR3 now. I'm definitely waiting before getting another GTX480 though...
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