This is a real issue that should be dealt with.
I too have to resort to lowering my res. to not be absolutely totally blind. I have a 2560x1600 native res, but run it at 1920x1200 to see the dots.
I have perfect vision, but online when my friend called out bogies, I couldn't see the enemy until they were much much closer, when the 3d model pops up. This range would be totally too close to be able to react properly. The single pixel at 2560x1600 (even on 30" monitor) is just too small for the eye to get a hold on.
Only indication that there were enemies around was the tracer firing I saw in the distance
.. And my friend yelling in TS "Can't you see them, they're right there!"
-Untamo